SEROTONIN – NOREPINEPHRINE REUPTAKE INHIBITORS
Selective Serotonin–norepinephrine reuptake inhibitors (SSNRIs) are a class of antidepressant drugs which are used in the treatment of major depressive disorder (MDD). They are sometimes also used to treat anxiety disorders, obsessive-compulsive disorder (OCD), attention-deficit hyperactivity disorder (ADHD), chronic neuropathic pain, and fibromyalgia syndrome (FMS), and for the relief of menopausal symptoms.
SSNRIs are monoamine reuptake inhibitors; specifically, they are inhibitors of the reuptake of serotonin and norepinephrine. These neurotransmitters are known to play an important role in mood. SSNRIs can be contrasted with the more widely used selective serotonin reuptake inhibitors (SSRIs), which act upon serotonin only.